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DiaMedBase ID |
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DMPCo132 |
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Medicinal Plant
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Calamintha officinalis
Moench |
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Plant part(s)
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Aerial parts |
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Objective |
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To investigate the effects
of a water extract from the aerial parts of Calamintha officinalis
Moench. |
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Journal Source
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J Pharm Pharmacol.
2004; 56(6):795-799 |
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Title
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Hypoglycaemic effect of
Calamintha officinalis Moench. in normal and streptozotocin-induced
diabetic rats |
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Authors
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Lemhadri A, Zeggwagh NA,
Maghrani M, Jouad H, Michel JB, Eddouks M |
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Address
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UFR PNPE BP 21, Errachidia,
52000, Morocco |
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Abstract
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The purpose of this study
was to investigate the effects of a water extract from the aerial
parts of Calamintha officinalis Moench., after either a single dose or
daily oral administration for 15 days, on plasma blood glucose
concentrations and basal insulin levels in normal and streptozotocin-induced
diabetic rats (STZ diabetic rats). The results clearly demonstrated
the hypoglycaemic effect of this plant extract in both normal and STZ
diabetic rats. In addition, no changes were observed in basal plasma
insulin concentrations after treatment with this plant in normal or
STZ diabetic rats, indicating that the underlying mechanism of the
plant's pharmacological action seems to be independent of insulin
secretion. We conclude that the aqueous C. officinalis extract
exhibits a significant hypoglycaemic effect in normal and STZ diabetic
rats without affecting basal plasma insulin concentrations, and
supports, therefore, its traditional use by the Moroccan population. |
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Diseases |
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Disease Link |
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