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DiaMedBase ID |
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DMPCe142 |
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Medicinal Plant
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Casearia esculenta |
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Plant part(s)
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Roots |
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Objective |
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To evaluate the role of
the Casearia esculenta on glycoprotein components in streptozotocin-induced
diabetic rats |
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Journal Source
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Pharmazie.
2005; 60(3):229-232 |
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Title
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Influence of Casearia
esculenta root extract on glycoprotein components in streptozotocin
diabetic rats |
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Authors
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Prakasam A, Sethupathy S,
Pugalendi KV |
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Address
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Department of
Biochemistry, Faculty of Science, Rajah Muthiah Medical College and
Hospital, Annamalai University, Annamalainagar, Tamilnadu, India |
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Abstract
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The present study was
aimed to evaluate the role of the indigenous antidiabetic medicinal
plant Casearia esculenta on glycoprotein components in streptozotocin-induced
diabetic rats in plasma, liver, kidney and cardiac tissues.
Streptozotocin injection (50 mg/kg body weight) caused massive
elevation of glycoprotein components such as hexose, hexosamine,
sialic acid and fucose in plasma and tissues of diabetic control and
experimental animals. Oral administration of C. esculenta root extract
(200 and 300 mg/kg body weight) for 45 days significantly reverted the
hexose, hexosamine, sialic acid and fucose levels to near normal
values. These results suggest a normalizing effect of C. esculenta on
glycoprotein components in STZ diabetic rats |
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Diseases |
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Disease Link |
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