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DiaMedBase ID |
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DMPCp175 |
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Medicinal Plant
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Cirsium pascuarense |
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Plant part(s)
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plant
extracts |
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Objective |
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To
test the change in blood glucose levels in normal and diabetic mice |
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Journal Source
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Phytother
Res,
2001; 15(6):552-554 |
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Title
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Effect of Cirsium pascuarense on blood glucose levels of
normoglycaemic and alloxan-diabetic mice |
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Authors
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Perez
Gutierrez RM, Ramirez E, Vargas R |
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Address
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Laboratorio de Investigacion de
Productos Naturales, Escuela Superior de Ingenieria Quimica e
Industrias Extractivas IPN, Punto Fijo 16 Col Torres Lindavista, CP.
07750, D.F., Mexico. dmex@dfl.telmex.net.mx |
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Abstract
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Blood glucose levels of normal and
alloxan-treated diabetic mice were determined after i.p.
administration of various doses of the hexane, chloroform and methanol
extracts of Cirsium pascuarense. From the data obtained, it is
concluded that the i.p. administration of 100, 150 and 200 mg/kg of
hexane extract of this plant produced a significant hypoglycaemic
effect in normal as well as in diabetic mice. In addition, the
extracts altered glucose tolerance in alloxan induced diabetic rats.
Chloroform and methanol extracts did not produce any significant
change in blood glucose levels. |
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Diseases |
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Disease Link |
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