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DiaMedBase ID |
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DMPAs009 |
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Medicinal Plant
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Achyranthes aspera |
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Plant part(s)
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Whole plant |
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Objective |
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To study the blood glucose levels of
normal and alloxan diabetic rabbits |
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Journal Source
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Journal of Ethnopharmacology
1991; 31(1):49-57 |
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Title
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Evaluation of the hypoglycaemic
effect of Achyranthes aspera in normal and alloxan-diabetic rabbits
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Authors
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Muhammad Shoaib Akhtar and Javed Iqbal
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Address
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Department of Physiology and
Pharmacology, University of Agriculture, Faisalabad-38040, Pakistan |
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Abstract
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Blood glucose levels of normal and
alloxan diabetic rabbits were determined after oral administration of
various doses of Achyranthes aspera powdered whole plant and certain
aqueous and methanolic extracts. Oral administration of 2, 3 and 4
g/kg of A. aspera powder produced a significant dose-related
hypoglycaemic effect in normal as well as in diabetic rabbits. The
water and methanol extracts also decreased blood glucose levels in
normal and alloxan diabetic rabbits. A 7-day acute toxicity study in
rabbits did not reveal any adverse or side effects of this folk
medicine at dosages up to 8 g/kg orally. It is possible that the plant
could act by providing certain necessary elements like calcium, zinc,
magnesium, manganese and copper to the beta-cells.
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Diseases |
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Disease Link |
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