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DiaMedBase ID |
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DMPAh073 |
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Medicinal Plant
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Artemisia herba alba |
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Plant part(s)
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Aerial parts |
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Objective |
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To study the
hypoglycaemic effect of Artemisia herba alba |
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Journal Source
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J Ethnopharmacol.
1994; 43(3):167-171 |
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Title
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Hypoglycaemic effect
of Artemisia herba alba. II. Effect of a valuable extract on some
blood parameters in diabetic animals |
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Authors
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al-Shamaony L, al-Khazraji
SM, Twaij HA |
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Address
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Department of
Pharmacology and Toxicology, College of Pharmacy, University of
Baghdad, Iraq |
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Abstract
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is widely used in
Iraqi folk medicine for the treatment of diabetes mellitus. However,
very few scientific and medical studies were carried out to assess the
efficacy and toxicity of A. herba alba. In this study feeding diabetic
rats and rabbits with 0.39 g/kg body weight of the aqueous extract of
the aerial parts of the plant for 2-4 weeks shows a significant
reduction in blood glucose level, prevents elevation of glycosylated
haemoglobin level and possesses a hypoliposis effect, in addition to
the protection against body weight loss of diabetic animals. |
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Diseases |
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Disease Link |
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DiaMedBase ID |
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DMPAp074 |
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Medicinal Plant
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Artemisia pallens Wall |
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Plant part(s)
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Aerial parts |
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Objective |
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To study the effect
of Artemisia pallens Wall. on blood glucose levels in normal and
alloxan-induced diabetic rats |
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Journal Source
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J Ethnopharmacol.
1996; 50(1):13-17 |
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Title
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Effects of Artemisia
pallens Wall. on blood glucose levels in normal and alloxan-induced
diabetic rats |
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Authors
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Subramoniam A,
Pushpangadan P, Rajasekharan S, Evans DA, Latha PG, Valsaraj R |
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Address
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Division of
Ethnopharmacology, Tropical Botanic Garden and Research Institute,
Palode, Kerala, India |
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Abstract
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Oral administration
of the methanol extract of the aerial parts of Artemisia pallens Wall.
(used in Indian folk medicine for the treatment of diabetes mellitus)
led to significant blood glucose lowering effect in glucose-fed
hyperglycaemic and alloxan-induced diabetic rats. This effect of the
extract was dose dependent and significant at 100 mg/kg level in
glucose-fed rats. In fasted normal rats, the extract caused a moderate
hypoglycaemic effect at a higher dose (1000 mg/kg). The water extract
(1000 mg/kg) was inactive. |
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Diseases |
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Disease Link |
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DiaMedBase ID |
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DMPAh075 |
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Medicinal Plant
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Trigonella
foenum-graecum L. (Leguminosae), Globularia alypum L. (Globulariaceae),
Artemisia herba-alba Asso. (Compositae), Citrullus colocynthis
(L.) Schrad. (Cucurbitaceae) and Tetraclinis articulata Benth.
(Cupressaceae) |
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Plant part(s)
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Aerial parts |
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Objective |
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To study the effect of
plants to treat diabetes in oritenal Morocco |
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Journal Source
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J Ethnopharmacol.
1997; 58(1):45-54 |
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Title
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Phytotherapy of
hypertension and diabetes in oriental Morocco |
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Authors
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Ziyyat A, Legssyer A,
Mekhfi H, Dassouli A, Serhrouchni M, Benjelloun W |
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Address
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Department of Biology,
University Mohamed the First, Faculty of Sciences, Oujda, Morocco |
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Abstract
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In order to select the
main medicinal plants used in folk medicine to treat arterial
hypertension and/or diabetes, a survey was undertaken in different
areas of oriental Morocco. The patients (370 women and 256 men) were
divided into three groups: diabetics (61%), hypertensives (23%) and
hypertensive diabetic persons (16%). On average, 67.51% of patients
regularly use medicinal plants. This proportion is perceptibly the
same in all groups and does not depend on sex, age and socio-cultural
level. This result shows that phytotherapy is widely adopted in
northeastern Morocco. For diabetes, 41 plants were cited, of which the
most used were Trigonella foenum-graecum L. (Leguminosae), Globularia
alypum L. (Globulariaceae), Artemisia herba-alba Asso. (Compositae),
Citrullus colocynthis (L.) Schrad. (Cucurbitaceae) and Tetraclinis
articulata Benth. (Cupressaceae). In the hypertension's therapy 18
vegetal species were reported, of which the most used were Allium
sativum L. (Liliaceae), Olea europea L. (Oleaceae), Arbutus unedo L. (Ericaceae),
Urtica dioica L. (Urticaceae) and Petroselinum crispum A.W. Hill (Apiaceae).
Among the 18 species used for hypertension, 14 were also employed for
diabetes. Moreover, these two diseases were associated in 41% of
hypertensives. These findings suggest that hypertension observed in
this region would be in a large part related to diabetes. |
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Diseases |
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Disease Link |
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DiaMedBase ID |
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DMPAr076 |
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Medicinal Plant
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Artemisia
roxburghiana, Salvia coccinia, Monstera deliciosa, Abies pindrow,
Centaurea iberica, Euphorbia helioscopia, Bauhinia variegate, Bergenia
himalacia, Taraxacum officinale, Viburnum foetens, Adhatoda vasica,
Cassia fistula, Chrysanthemum leucanthemum, Morus alba, Plectranthus
rugosus, Peganum harmala and Olea ferruginea |
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Plant part(s)
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Whole plant |
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Objective |
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To study the effects
of medicinal plants on diabetes |
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Journal Source
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Phytother Res,
2004; 18(1):73-77 |
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Title
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The effect of
medicinal plants of Islamabad and Murree region of Pakistan on insulin
secretion from INS-1 cells |
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Authors |
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Hussain Z, Waheed A,
Qureshi RA, Burdi DK, Verspohl EJ, Khan N, Hasan M |
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Address |
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Department of
Chemistry, Quaid-i-Azam University, Islamabad Pakistan. chem63@yahoo.com |
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Abstract |
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In vitro testing of
the extracts of medicinal plants collected from Islamabad and the
Murree region on insulin secretagogue activity was carried out. Dried
ethanol extracts of all plants (ZH1-ZH19) were dissolved in ethanol
and DMSO, and tested at various concentrations (between 1 and 40
microg/mL) for insulin release from INS-1 cells in the presence of 5.5
mM glucose. Glibenclamide was used as a control. Promising insulin
secretagogue activity in various plant extracts at 1, 10, 20 and 40
microg/mL was found, while in some cases a decrease in insulin
secretion was also observed. Artemisia roxburghiana, Salvia coccinia
and Monstera deliciosa showed insulin secretagogue activity at 1
microg/mL (p < 0.05) while Abies pindrow, Centaurea iberica and
Euphorbia helioscopia were active at 10 microg/mL (p < 0.05). Extracts
of Bauhinia variegata and Bergenia himalacia showed effects at 20
microg/mL (p < 0.05), and Taraxacum officinale and Viburnum foetens at
40 microg/mL (p < 0.05). Insulin secretagogue activity could not be
detected in the extracts of Adhatoda vasica, Cassia fistula,
Chrysanthemum leucanthemum, Morus alba, Plectranthus rugosus, Peganum
harmala and Olea ferruginea. The results suggest that medicinal plants
of Islamabad and the Murree region of Pakistan may be potential
natural resources for antidiabetic compounds. |
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Diseases |
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Disease Link |
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DiaMedBase ID |
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DMPAh077 |
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Medicinal Plant
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Artemisia herba alba |
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Plant part(s)
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Aerial parts |
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Objective |
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To study the
hypoglycemic activity of
Artemisia herba alba |
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Journal Source
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J Ethnopharmacol.,
1988; 24(2-3):123-126 |
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Title
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Hypoglycemic
activity of Artemisia herba alba |
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Authors
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Twaij HA, Al-Badr AA |
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Address
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Department of
Pharmacognosy and Pharmacology, Biological Research Centre, Baghdad,
Iraq |
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Abstract
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Artemisia herba alba
has been widely used in Iraqi folk medicine for the treatment of
diabetes mellitus. Oral administration of an aqueous extract (0.39
g/kg) of the aerial parts of this plant to normoglycemic and to
alloxan-diabetic rabbits produced significant hypoglycemic activity,
which was consistent and time-dependent. |
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Diseases |
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Disease Link |
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DiaMedBase ID |
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DMPAd078 |
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Medicinal Plant
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Bearberry
(Arctostaphylos uva-ursi), golden seal (Hydrastis canadensis),
mistletoe (Viscum album), tarragon (Artemisia dracunculus),
bayberry (Cinnamomum tamala), meadowsweet (Filipendula ulmaria), senna
(Cassia occidentalis) |
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Plant part(s)
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Herbal mixture of
all plants |
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Objective |
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To study blood
glucose levels |
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Journal Source
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Acta Diabetol Lat.,
1989; 26(1):51-55 |
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Title
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Evaluation of
traditional plant treatments for diabetes: studies in streptozotocin
diabetic mice |
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Authors
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Swanston-Flatt SK,
Day C, Bailey CJ, Flatt PR |
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Address
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Department of
Biological and Biomedical Sciences, University of Ulster, Coleraine,
U.K |
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Abstract
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Seven
plants and a herbal mixture used for traditional treatment of diabetes
were studied in streptozotocin diabetic mice. The treatments were
supplied as 6.25% by weight of the diet for 9 days. Consumption of
diets containing bearberry (Arctostaphylos uva-ursi), golden seal (Hydrastis
canadensis), mistletoe (Viscum album) and tarragon (Artemisia
dracunculus) significantly reduced the hyperphagia and polydipsia
associated with streptozotocin diabetes, but bayberry (Cinnamomum
tamala), meadowsweet (Filipendula ulmaria), senna (Cassia occidentalis)
and the herbal mixture did not alter these parameters. Bearberry,
mistletoe and tarragon retarded the body weight loss but none of the
eight treatments significantly altered plasma glucose or insulin
concentrations. These studies suggest that bearberry, golden seal,
mistletoe and tarragon may counter some of the symptoms of
streptozotocin diabetes without, however, affecting glycemic control. |
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Diseases |
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Disease Link |
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DiaMedBase ID |
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DMPAh079 |
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Medicinal Plant
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Artemisia herba alba |
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Plant part(s)
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Leaves
and Bark |
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Objective |
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To study the
hypoglycaemic effect of Artemisia herba alba |
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Journal Source
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J Ethnopharmacol.
1993; 40(3):163-166 |
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Title
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Hypoglycaemic effect
of Artemisia herba alba. I. Effect of different parts and influence of
the solvent on hypoglycaemic activity |
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Authors
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al-Khazraji SM, al-Shamaony
LA, Twaij HA |
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Address
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Department of
Pharmacology and Toxicology, College of Pharmacy, University of
Baghdad, Iraq |
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Abstract
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Artemisia herba alba
is widely used in Iraqi folk medicine for the treatment of diabetes
mellitus. Oral administration of 0.39 g/kg body weight of the aqueous
extract of the leaves or barks produced a significant reduction in
blood glucose level, while the aqueous extract of roots and the
methanolic extract of the aerial parts of the plant produce almost no
reduction in blood glucose level. The extract of the aerial parts of
the plant seem to have minimal adverse effect and high LD50 value. |
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Diseases |
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Disease Link |
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