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DiaMedBase ID |
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DMPLb378 |
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Medicinal Plant
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Loranthus begwensis,
Citrus limon, Vernonia amygdalina |
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Plant part(s)
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Whole plant |
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Objective |
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To study the effect of an
aqueous extract in lowering blood sugar levels |
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Journal Source
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Phytotherapy Research,
1998; 11(2):171-173 |
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Title
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Metabolic and Renal
Changes Following the Ingestion of African Mistletoe Extract in Rats |
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Authors
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D. K. Obatomi, A. A. A.
Oye, Z. N. Jangber, V. J. Temple |
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Address
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Department of
Biochemistry, Faculty of Medical Science, University of Jos, P. M. B.
2084, Jos, Nigeria |
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Abstract
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The effect of an aqueous
extract of African mistletoe (Loranthus begwensis) from two
host plants (Citrus limon [Cl-mistletoe] or Vernonia
amygdalina [Va-mistletoe]) was studied in male Wistar rats treated
orally with either 1.32, 13.2 or 26.4 g/kg per day for 7 days. A
significant dose-dependent reduction (p<0.01) in the
serum glucose and cholesterol was obtained with both extracts,
accompanied by a reduction of urine flow rate and serum creatinine.
Increases in urinary enzymes and protein excretion were dose-related
and dependent on the source of extracts. Mistletoe extract
irrespective of source appears to lower the blood sugar level offering
the potential for clinical use of the ingredients of its extracts. |
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Diseases |
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Disease Link |
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DiaMedBase ID |
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DMPLl379 |
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Medicinal Plant
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Loranthus begwensis |
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Plant part(s)
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Leaves |
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Objective |
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To study the aqueous
extract of leaves of Loranthus bengwensis in non-diabetic and
streptozotocin-induced diabetic rats |
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Journal Source
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Journal of
Ethnopharmacology
1994;
43(1):13-17 |
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Title
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Anti-diabetic properties
of the African mistletoe in streptozotocin-induced diabetic rats
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Authors
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David K. Obatomi, Ewenodere O. Bikomo
and Victor J. Temple |
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Address
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Department of
Biochemistry, Faculty of Medical Sciences, University of Jos, P.M.B.
2084, Jos, Nigeria |
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Abstract
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The African mistletoe,
Loranthus bengwensis L. (Loranthaceae), has been widely used in
Nigerian folk medicine to treat diabetes mellitus. The aqueous extract
or infusion (1.32 g/kg per day) of the leaves of this plant parasitic
on lemon, Citrus limon (L.) Brum f. (Rutaceae), guava, Psidium guajava
L. (Myrtaceae) and jatropha, Jatropha curcas L. (Euphorbiaceae),
respectively, were supplied ad libitum to separate groups of both
non-diabetic and streptozotocin-induced diabetic rats, as their only
source of fluid for a period of 28 days. The infusions of mistletoe
parasitic on both lemon and guava trees significantly decreased serum
glucose levels in non-diabetic (P < 0.05) and diabetic (P < 0.001)
rats, whereas that prepared from mistletoe parasitic on jatropha did
not. The data indicate that African mistletoe possesses significant
anti-diabetic activity in streptozotocin-induced diabetic rats; its
anti-diabetic activity appears to be highly dependent on the host
plant species. |
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Diseases |
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Disease Link |
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