|
|
|
|
DiaMedBase ID
|
|
DMPPt506 |
|
Medicinal Plant
|
|
Pedilanthus tithymaloides |
|
Plant part(s)
|
|
Lectin |
|
Objective
|
|
To investigate diabetes mellitus using
galactose specific lectin from P. tithymaloides |
|
Journal Source
|
|
Indian J Exp Biol.
1998; 36(4):426-428 |
|
Title
|
|
Hemagglutination pattern of
galactose specific lectin from Pedilanthus tithymaloides in diabetes
mellitus |
|
Authors
|
|
Nagda KK, Deshmukh B |
|
Address
|
|
Department of Biochemistry, Dr. V. M.
Medical College, Solapur, India |
|
Abstract
|
|
The usefulness of a galactose specific
lectin from P. tithymaloides was examined to study the
hemagglutination pattern in 193 patients with diabetes mellitus out of
which 34 cases were of insulin dependent. A control of 72 normal
subjects was also included. The hemagglutination titre against a
partially purified lectin from P. tithymaloides of control group
ranged from 9.1 to 170 units per mg protein with a mean value of 54
units per mg protein. Significantly low titre was observed in the
cases with insulin dependent diabetes mellitus, while non-insulin
dependent diabetes mellitus cases did not show any significant change.
Further significant reduction in the titre in insulin dependent
diabetes mellitus group was shown to occur along with the increased
duration of the diabetic condition, reflecting measurable erythrocyte
surface alterations. |
|
Diseases |
|
Disease Link |
|
