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DiaMedBase ID |
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DMPPd537 |
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Medicinal Plant
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Prunus davidiana |
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Plant part(s)
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Stems |
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Objective |
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To study the hypoglycemic effect in
rats |
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Journal Source
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Planta Med. 1991;
57(3):208-211 |
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Title
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Improvement of hyperglycemia and
hyperlipemia in streptozotocin-diabetic rats by a methanolic extract
of Prunus davidiana stems and its main component, prunin |
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Authors
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Choi JS, Yokozawa T, Oura H. |
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Address
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Department of Nutrition and Food
Sciences, National Fisheries University of Pusan, Korea |
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Abstract
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Blood glucose and total lipid levels in
rats with streptozotocin-induced diabetes were determined after
intraperitoneal administration of a methanolic extract of Prunus
davidiana Fr. stems and its main component, prunin (= naringenin
7-O-beta-D-glucoside). From the data obtained it was concluded that
intraperitoneal administration of the methanolic extract and prunin
produced a significant hypoglycemic effect. Total blood lipids were
also decreased by these substances. Thus, it is suggested that this
methanolic extract contains one or more hypoglycemic principles
including the main flavanone glycoside, prunin, which can
significantly reduce the levels of blood glucose and total lipids in
streptozotocin-diabetic rats. |
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Diseases |
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Disease Link |
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