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DiaMedBase ID |
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DMPPg555 |
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Medicinal Plant
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Punica granatum |
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Plant part(s)
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Seeds |
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Objective |
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To study the hypoglycaemic activity of
Punica granatum seed extract on rats made diabetic by
streptozotocin |
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Journal Source
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Phytotherapy Research,
2001; 15(7)628-629 |
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Title
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Studies on the hypoglycaemic
activity of Punica granatum seed in streptozotocin induced diabetic
rats |
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Authors
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Asish K. Das, Subhash C. Mandal, Sanjay
K. Banerjee, Sanghamitra Sinha, B. P. Saha, M. Pal |
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Address
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Department of Pharmaceutical
Technology, Faculty of Engineering and Technology, Jadavpur
University, Calcutta - 700 032, India |
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Abstract
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The hypoglycaemic activity of Punica
granatum Linn. (Family Punicaceae) seed extract on rats made
diabetic by streptozotocin (STZ) was investigated. The methanol
extract of the seed at doses of 300 and 600 mg/kg, and chlorpropamide
200 mg/kg was administered to STZ diabetic rats. The seed extract
(150, 300 and 600 mg/kg, orally) caused a significant reduction of
blood glucose levels in STZ induced diabetic rats by 47% and 52%,
respectively, at the end of 12 h. |
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Diseases |
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Disease Link |
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DiaMedBase ID |
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DMPPg556 |
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Medicinal Plant
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Punica granatum |
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Plant part(s)
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Flowers |
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Objective |
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To treat diabetes
mellitus in Unani medicine |
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Journal Source
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J Ethnopharmacol,
2000; 70(3):309-314 |
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Title
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Effect of Punica granatum Linn.
(flowers) on blood glucose level in normal and alloxan-induced
diabetic rats |
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Authors
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Jafri MA, Aslam M,
Javed K, Singh S |
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Address
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Department of
Ilmul Advia, Faculty of Medicine (Unani), Jamia Hamdard, -110 062, New
Delhi, India |
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Abstract
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'Gulnar farsi', male abortive flowers of
Punica granatum L., are used for the treatment of diabetes mellitus in
Unani medicine. Oral administration of its aqueous-ethanolic (50%,
v/v) extract led to significant blood glucose lowering effect in
normal, glucose-fed hyperglycaemic and alloxan-induced diabetic rats.
This effect of the extract was maximum at 400 mg/kg, b.w. |
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Diseases |
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Disease Link |
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